Aging and Public Health: From Molecular Changes to Physiological Challenges

Authors

  • Siamak Takesh University of Coimbra, Faculty of Sport Sciences and Physical Education, Coimbra, Portugal
  • Ebrahim Banitalebi Department of Sport Sciences, Shahrekord University, Shahrekord, Iran.

DOI:

https://doi.org/10.22034/LSSJ.2025.143

Keywords:

again, gut microbiome, cognitive decline, aerobic training, sarcopenia

Abstract

This review examines the aging process from molecular, cellular, and physiological perspectives. Aging is characterized by a gradual decline in cellular and systemic functions due to disruptions in molecular mechanisms such as DNA damage, telomere shortening, and mitochondrial dysfunction. These disturbances lead to structural and functional alterations in vital organs, including the heart, arteries, kidneys, and brain, which in turn elevate the risk of cardiovascular diseases, cancers, cognitive disorders, and other age-related conditions. Furthermore, improvements in nutrition, lifestyle, and exercise have been shown to mitigate the negative effects of aging, suggesting promising strategies for enhancing quality of life in older populations.

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Published

2025-04-13

How to Cite

Takesh, S., & Banitalebi, E. . (2025). Aging and Public Health: From Molecular Changes to Physiological Challenges. Life Sciences Student Journal, 3(2), 1–13. https://doi.org/10.22034/LSSJ.2025.143